A Review Of stem cell therapy
With the idea that a more fast cell cycle is really a critical part of pluripotency, reprogramming effectiveness may be improved. Strategies for improving upon pluripotency through manipulation of cell cycle regulators contain: overexpression of Cyclin D/Cdk4, phosphorylation of Sox2 at S39 and S253, overexpression of Cyclin A and Cyclin E, knockdo